Emisphere Technologies, Inc.
May 6, 2011

Emisphere Technologies, Inc. Announces First Quarter 2011 Earnings Conference Call

Conference Call/Webcast to be Held Tuesday, May 10, 2011 at 10:00 AM EDT

CEDAR KNOLLS, N.J., May 6, 2011 (GLOBE NEWSWIRE) -- Emisphere Technologies, Inc. (OTCBB:EMIS) announced today that management will host a conference call to discuss the Company's financial and operational results for the First Quarter ended March 31, 2011 on Tuesday, May 10, 2011 at 10:00 AM EDT. A press release will be issued prior to market open.

The live webcast of the conference call can be accessed through the company's web site at: www.emisphere.com. The live conference call dial-in number is: 1-888-318-7450 (United States and Canada) or 1-719-325-2202 (International). In addition, an archive of the webcast can be accessed through the same link and an audio replay of the call will be available beginning at 1:00 PM EDT through midnight on May 24, 2011 by calling 1-888-203-1112 (United States and Canada) or 1-719-457-0820 (International). The conference replay PIN is 6622372.

About Emisphere Technologies, Inc.

Emisphere is a biopharmaceutical company that focuses on a unique and improved delivery of pharmaceutical compounds, medical foods and dietary supplements using its Eligen® Technology. These molecules and compounds could be currently available or in development. Such molecules are usually delivered by injection; in many cases, their benefits are limited due to poor bioavailability, slow on-set of action or variable absorption. The Eligen® Technology can be applied to the oral route of administration as well other delivery pathways, such as buccal, rectal, inhalation, intra-vaginal or transdermal. The company's website is: www.emisphere.com.

CONTACT: Michael R. Garone - Interim CEO, CFO

         973.532.8005 or mgarone@emisphere.com



         Karen Kelsch - Assistant Manager, Communications

         973.532.8101 or kkelsch@emisphere.com
Source: Emisphere Technologies, Inc.

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